Notes about the figures:

Left. Basic anatomy of the forearm. The forearm has two bones, the radius and the ulna. The interosseous membrane (IM) is a thin sheet of
tissue that connects them. The IM is important because it creates stability and distributes weight across the two bones when the arm is being
used. In OI5, the IM becomes calcified, meaning that soft tissue is replaced with calcium. The IM becomes stiff, and patients have difficulty
rotating their palms up and down. The arm becomes painful and unstable, and the head of the radius (top left in drawing) may slip out of place.

Center. An X-ray of a person with a normal interosseous membrane. Source: Radiopedia (see radiopedia).

Right. An X-ray of an 11-year-old girl with OI type V. The X-ray shows calcification of her interosseous membrane. Source: below.

Source: Fujino T et al. (2010) Sporadic osteogenesis imperfecta type V in an 11-year-old Japanese girl. J Orthop Sci 15(4):589-593.

Figure reprinted with permission from Elsevier. Abstract on publisher website.   Abstract on PubMed.

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Page last modified on 22 January 2019.